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Why does hydrcortisone + pencillin not work in combination? The hydrocortisone inactivates the penicillin how?
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which clinical situation are you talking about? which way od administration?
The question doesn't make any sense, they should have no effect on eachother. The only thing i would consider in the combination, that Cortisol is a stress hormone which has immunosuppressant properties, therefore might not be the best combination. What makes you think they do not work in combination?
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