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OpenStudy (anonymous):
Why do weak bonds form between substrates and enzymes and not covalent bonds? What factors contribute to the formation of these bonds in the enzyme-substrate complex?
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OpenStudy (anonymous):
because after the reaction occurs product must leave the active site.. if it was a covalent bond then it would be difficult to break the covalent bond.... presence of carbonyl group and amino gp is responsible for H-bonding....
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