Question

You identify a mutation in the factor binding center on the ribosome which causes it to no longer be able to hydrolyze GTP. Upon further analysis, you discover that it is able to hydrolyze ATP instead. Describe all of the translation factors that would need to be able to bind to ATP instead of GTP for this mutant ribosome to be able to function in the cell. In your answer, make sure you also describe the normal function of the factor binding center and where it is located in the ribosome.