Question

how do the plaque forms in the brain?

Answer 1

Due to a genetic mutation and/or environmental factors, toxic amyloid-beta peptides accumulate in the brain which in turn threaten healthy nerve cells in the surrounding areas. Once these toxic peptides are produced, a structure called plaque forms in the brain which leads to Alzheimer’s.

Answer 2

Take a look at this graphical: http://is.gd/uCXf0U