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How does the lymphatic system interact with the circulatory system?
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When blood passed from the arteries to the arteriole and into capillaries, some of the plasma usually leaks out as tissue fluid. A portion of this diffuses into the lymphatic vessels, along with: lymphocytes and phagocytes and other cells of the immune system. This then drain into the lymph nodes where pathogens are attacked and killed and further immunological reaction is initiated. This usually results in a swollen lymph node. The lymphatic fluid then rejoins the circulatory system by draining into a vein.
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