A bacterium undergoes mutation caused by an antibiotic. Specifically, the gene with the sequence AUGCCCACCCGA undergoes a frameshift mutation. Which of these sequences represents the mutated gene?

Question

thomaster · Answer

Can you post the options too?

thomaster · Answer

I'll give an example of a frameshift mutation.

The original sequence is:           AUG|CCC|ACC|CGA
So the coding strand would be  UAC|GGG|UGG|GCU  (the | represent the frames (codons)

When let's say when deletion of the second base (U) occurs,
The original sequence would be AGC|CCA|CCC|GA
the coding strand will be            UCG|GGU|GGG|CU

You see the frames are now different, The first frame used to be UAC (Tyrosine)
Now it is UCG (Serine). So entirely different amino acids are produced.

I think you can recognize the mutated gene with this information.

anonymous · Answer

thank you

anonymous · Answer

A) AUGGCCACCCGA
B) AUGACCCACCCGA
C) AUGCCCUCCCGU


the answer choices and im still confused