The incidence of cystic fibrosis, a recessive genetic disorder in the Caucasian population of United States, is 1 in every 2,500 individuals. Find the number of heterozygous carriers.
(p + q = 1, p2 + 2pq + q2 = 1)
A. 0.0392
B. 0.0254
C. 0.045

Question

The incidence of cystic fibrosis, a recessive genetic disorder in the Caucasian population of United States, is 1 in every 2,500 individuals. Find the number of heterozygous carriers.
(p + q = 1,  p2 + 2pq + q2 = 1)
A. 0.0392
B. 0.0254
C. 0.045

anonymous · Answer

rate of carriers is 1/25 
2qp = 1/25 
then we can solve it to give us a q = 0.02 and p = 0.98  the qp = 0.0392