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MIT OCW Biology
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how do you tell if an amino acid is hydrophobic or hydrophillic?
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You look at the side chain :) http://en.wikipedia.org/wiki/Proteinogenic_amino_acid#Side_chain_properties
If you see lots of non polar bonds like C-H, then that indicates that the amino acid is highly hydrophobic. If you see lots of polar bonds like O-H, N-H, then the amino acid is highly hydrophillic. Hope this helps :)
This will depend of the structure of the molecule, it's atomic constitution, display and it's distribution of eletrons...
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