explain why fsh does not bind to a lh receptor

Question

shrutipande9 · Answer

every receptor is signalling molecule specific...so lh receptor would bind to lh only and not follicle stimulating hormone. dis is what i think....but i m trying to search between d structural differences which avoid dis unusual bindin

shrutipande9 · Answer

the receptor of these 2 molecules are very very same...both gpcr both acivate cAMP pathway...the difference is just the size....maybe this causes the specificity....

shrutipande9 · Answer

am i near 2 what u want?

anonymous · Answer

i got the answer thxx for the help

shrutipande9 · Answer

could u share it here?

anonymous · Answer

because LH is not complimentary to FSH as Fsh has a shorter B-chain compared to Lh. Fsh has different primary structure and tertiary structure.

shrutipande9 · Answer

Cool! Thnx

anonymous · Answer

u r welcome :)