This is a long shot but has anyone ever heard of a molecular probe called "Three-way junction probe and Template Enhanced Hybridization Processes (TeHyP)"?

I've looked everywhere but i haven't found the reason for the melting temperature lowering upon hybridization of the target with the 2 complementary portions of the probe strands... If anyone knows why, i'd really appreciate it.

Question

This is a long shot but has anyone ever heard of a molecular probe called "Three-way junction probe and Template Enhanced Hybridization Processes (TeHyP)"?

I've looked everywhere but i haven't found the reason for the melting temperature lowering upon hybridization of the target with the 2 complementary portions of the probe strands... If anyone knows why, i'd really appreciate it.

abb0t · Answer

Never heard of this. If you find any information, do post. Sounds interesting.

abb0t · Answer

http://books.google.com/books?id=fN_Idpc30ngC&pg=PA115&lpg=PA115&dq=Template+Enhanced+Hybridization+Process&source=bl&ots=c977nzXZMT&sig=-kTHBg2w-jd75xqEUQlTei8jU38&hl=en&sa=X&ei=lhOMUt_LDcqv2QXn2oDoCw&ved=0CHcQ6AEwBw#v=onepage&q=Template%20Enhanced%20Hybridization%20Process&f=false

aaronq · Answer

haha thanks for the link, the paper it's talking about is actually one that I'm using for  a report. When i do find more about it, it'll post it up here.

anonymous · Answer

Can you help me with my question again?

aaronq · Answer

asking for help on other people's questions is rude.

abb0t · Answer

What a sneaky snake. Trying to pull a fast one. Haha.