A variety of treatments can cause cells to undergo apoptosis. You wish to know which of these treatments induce signals that are processed through Bid, Bax & Bak (Diagram below). You generate Bid-/- & Bax-/-Bak-/- mouse embryo fibroblasts (MEFs) & test them from apoptosis in response to several treatments, with the results show in the Table below. a) Based on these results, indicate where each of the signals enters the apoptotic pathway relative to Bid, Bax and Bak.

Question

A variety of treatments can cause cells to undergo apoptosis. You wish to know which of these treatments induce signals that are processed through Bid, Bax & Bak (Diagram below).  You generate Bid-/- & Bax-/-Bak-/- mouse embryo fibroblasts (MEFs) & test them from apoptosis in response to several treatments, with the results show in the Table below. a) Based on these results, indicate where each of the signals enters the apoptotic pathway relative to Bid, Bax and Bak.