Question

Hemophilia is a disease that causes uncontrollable bleeding. If a father has it, all of his daughters will be carriers of the disease, and about half of his sons will have the disease. An error in which macromolecule is the cause of hemophilia?

Answer 1

There are all sorts of mutations which cause haemophilia. One which is easy to understand is caused by changing a single base at the beginning of a codon for argenine (CGA) somewhere in the gene to give TGA. If you look back to the table higher up the page, you will find that TGA is a stop codon.

http://www.chemguide.co.uk/organicprops/aminoacids/dna6.html

Answer 2

this is a really good website ....im sure it will help u :)
http://www.nhlbi.nih.gov/health/health-topics/topics/hemophilia/causes.html