Consider the genetic association data of Table 6. (a) What does it mean in simple language? (b) Do you reject the hypothesis of no association between coronary artery disease and this SNP at the 0.01 significance level? Show your steps. (c) Is coronary artery disease associated with the SNP? Defend your answer. http://i.imgur.com/4Hiw2BY.png

Question

Consider the genetic association data of Table 6. (a) What does it mean in simple language? (b) Do you reject the hypothesis of no association between coronary artery disease and this SNP at the 0.01 significance level? Show your steps. (c) Is coronary artery disease associated with the SNP? Defend your answer.  http://i.imgur.com/4Hiw2BY.png

australopithecus · Answer

For a) I assume I just make a table of n_disease/n_total and n_control/n_total

How do I do part b?

australopithecus · Answer

also for a it would just require a brief description that the table is displaying if the presence of disease is linked to the individual having specific alleles

australopithecus · Answer

of a gene

australopithecus · Answer

This is a simple chi square analysis, would my Expected be 0.01? and observed would just be n_disease/n_total

australopithecus · Answer

oh oh I see what I'm doing wrong

australopithecus · Answer

oh I see what I did wrong