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Tay-Sachs is a recessive genetic disease (coded for by the T allele) that is always fatal in childhood. Healthy individuals have at least one N allele. Suppose that in a population of 10,000 adults, 2,000 have the NT genotype. ! How many adults have the NN genotype? Compute the allele frequencies in these adults’ gametes and the genotype frequencies in these adults’ zygotes. !
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