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Organic 18 Online
OpenStudy (anonymous):

Which of the following will undergo decatboxylation most easily? 1) butyric acid 2) Isobutyric Acid 3)Acetic acid 4) 2,2 dimethyl propanoic acid Why?

OpenStudy (abb0t):

You can eliminate option 4 first of all because you have the two methyl groups blocking from attack. therefore, making it costly in energy to decarboxylate.

OpenStudy (anonymous):

How to compare option 1 & 3?

OpenStudy (abb0t):

look at the stability of their carbanion intermediate.

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