Could someone please explain in simple terms what would happen if a eukaryotic cell had a damaged enhancer and what would be affected/changed in the gene regulation progress?

Question

anonymous · Answer

enhancer is the part that starts DNA transcription. So basically if your "start engine" is damaged, the gene might not work at all, or work in some weird way

blake4560 · Answer

okay.. to be honest, Biology is confusing somewhat. to my question early, would this mean that specific transcriptions would take over the gene expression or RNA polymerase wouldn't bind to the enhancer?

anonymous · Answer

polymerase wouldn't bind to it, most likely

blake4560 · Answer

also with this could you please your reason for your answer... I like to know why and not just have the answer told to me.. help appreciated!

anonymous · Answer

the way that transcription works is that if you have some protein (polymerase) attached to it. If that part of the gene is damaged, it is most likely disfigured, then the site that the protein bind with it is no longer available (because since it's disfigured, its shaped changed)

anonymous · Answer

or it is also possible that the protein can bind, but maybe it binds in a different place, or maybe since the chemical structure of the enhancer changed, the reaction may go differently than what it normally would

blake4560 · Answer

would the DNA-protein (mediator) bonds have anything to do with this? I know that  activator is a transcription protein that binds to an enhancer and the mediator protein connects the enhancer to the promoter region...

anonymous · Answer

I'm sorry, but I can't help you further. I'm majoring in chemistry, and the last bio class that I took is 9th grade in high school, so... I can only answer in the perspective of chemistry, but anything other than that is a hopeless cause :P

blake4560 · Answer

well... I thank you for taking the time to try to explain it. I really appreciated your help.. I think believe that I am closer to the answer! again thank you! :]

blake4560 · Answer

thanks... I am glad that I came. my brother recommended it to me because I am struggling with AP Biology.. he said that there were people who could help me whether it is explaining and such...