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OpenStudy (anonymous):

Which of the following body systems does the immune system rely on to provide the first line of the defense against pathogens? A. Integumentary system B. Nervous system C. Circulatory system D. Endocrine system

OpenStudy (deepika.comet):

Circulatory system - as it contains blood flowing and the antibodies are released into blood for destroying the attack of pathogen. ALL THE BEST.

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