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MIT OCW Biology
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OpenStudy (anonymous):
Because you are interested in studying how a particular secretory protein folds within the ER, you wish to determine whether BiP binds to the newly synthesized protein in ER extracts. You find that you can isolate some of the newly synthesized secretory protein bound to the BiP when ADP is added to the cell extract but not when ATP is added to the extract. Explain this result based on the mechanism for BiP binding to substrate.
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