Question

Members of the Mitogen-Activated Protein Kinase (MAPK) protein family are essential for many cellular responses to the extracellular environment. A MAPK protein becomes active after it becomes phosphorylated by a second kinase. These MAPKs contain a “ docking site” distant from the enzyme's active site that binds to conserved 10–15 amino acid “ docking motifs” found in a variety of proteins (see the Figure below). Docking motifs are found in proteins that bind MAPKs (scaffold proteins), proteins that are substrates of MAPKs, proteins that activate MAPKs by phosphorylating them (MAPK kinases),

Answer 1

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