Question

Predict the charge on the major species of the peptide Gly–Arg–Asp–Ala–Lys–Thr–Gln at pH 6.0

Answer 1

make a chart with the charges of the R groups of each amino acid then the\(\alpha\)-amino group and \(\alpha \)-carboxyl group for terminal amino acids.

you need to determine the charge on each of the R groups using the henderson hasselbalch equation (using the pKa's).