The clinical trial under consideration in this activity only affected somatic cells. Therefore, any modification to the individual would not be passed on to offspring. Consider the case 25 years in the future. One of our Pompe patients has successfully been treated with gene therapy and is living a very normal, happy life. He is married to a wonderful person, and they long to start a family. However, the man will pass mutations for Pompe along to his children. His wife has been tested and carries some of the mutations as well, although she does not exhibit symptoms of Pompe disease. What is yo

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