Question

Which software is Designed to prevent malicious software from accessing you computer ?

Answer 1

Antivirus or anti-virus software is such designed to prevent malicious software from accessing your computer

Answer 2

The use of Firewall can also perform the same task, by asking you the permission of accessing certain files. If a file is suspicious, you reject it.

Answer 3

Note in the question it says "malicious" from the french mal- meaning "bad" so any kind of anti-malware software, including anti-virus and firewalls.