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What is the role of DNA helicase during DNA replication?
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To unwind the duplex DNA. Helicase help to Unwind the double strand of DNA in order for replication to take place. DNA gyrase help to form negative supercoil to aid the Unwinding.
DNA helicase continues to unwind the DNA forming a structure called the replication fork, which is named for the forked appearance of the two strands of DNA as they are unzipped apart. The process of breaking the hydrogen bonds between the nucleotide base pairs in double-stranded DNA requires energy.
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