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OpenStudy (daniah7414201120022011):
Sickle cell disease is caused by a??? need help on this one plzz
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OpenStudy (mightychondrion):
Sickle cell anemia is caused by a base substitution mutation. It's a change in the 6th codon for the beta chain of hemoglobin, which is changed from GAG to GTG on the non-coding DNA strand and on the mRNA codon it's changed from GAG to GUG. This results in a change in the amino acid produced since now Valine is produced instead of Glutamic acid.
OpenStudy (anonymous):
^
OpenStudy (ashash146):
Is there multiple choice:)?
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