Question

Orgo II Mini-Tutorial: Bayer-Villiger Oxidation

Answer 1

\({\bf{Overview:}}\) mCPBA + aldehyde/ketone will insert another oxygen atom next to the C=O group. If both sides of the aldehyde/ketone are diff, the oxygen will go towards the more substituted side (via carbocation stability)

Answer 2

\({\bf{Mechanism:}}\)

Answer 3

the C=O bond on the peroxy group also is susceptible to protonation, and after that, the electron pushing will naturally follow to stabilize the resulting positive charge

Answer 4

Anyway, that's the end of my tutorial, I hope it was a helpful resource. Source material is Organic Chemistry 12th edition by Solomons, et. al.