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Orgo II Tutorial: Amide Synthesis
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there's a lot of synthesis methods for amides so will be creating a separate tutorial for amide reactions \({\bf{Basic~Mechanism:}}\) |dw:1540950396865:dw|
using a similar mechanism, you can react an anhydride to get 1 unit of the amide and 1 unit of the carboxylate salt. note: this requires 2 units of the amine. |dw:1540951018195:dw|
special case: if you have a cyclic product containing both amine and OH groups |dw:1540951777087:dw|
|dw:1540952651171:dw|
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Anyway, that's the end of my tutorial, I hope it was a helpful resource. Source material is Organic Chemistry 12th edition by Solomons, et. al.
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