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Orgo II Tutorial: Amide Reactions
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\({\bf{Hydrolysis:}}\) *** note*** requires heat; can work with either aqueous acid or aqueous base can work with either acid or base acid ---> produces carboxylic acid, while base produces the carboxylate salt
\({\bf{Mechanisms:}}\) same general idea for both acid and base hydrolysis (attack central C with water/base) |dw:1540954668490:dw|
|dw:1540955095069:dw|
\({\bf{Dehydration:}}\) using P2O5 (technically the molecule is actually P4O10 but it's often written as P2O5) will make nitriles |dw:1540955734405:dw|
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Anyway, that's the end of my tutorial, I hope it was a helpful resource. Source material is Organic Chemistry 12th edition by Solomons, et. al.
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