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Orgo II Mini-Tutorial: HVZ reaction
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\({\bf{Overview:}}\) the Hell-Volhard-Zelinski (yes, that's what it's actually called) reaction involves a a carboxylic acid (with alpha hydrogens) reacting with phosphorus to halogenate the acid at the alpha carbon |dw:1542329033424:dw|
|dw:1542329790348:dw|
\({\bf{Synthetic~Applications:}}\) this method can be used to synthesize alpha-hydroxy acids and alpha-amino acids |dw:1542330150854:dw|
Anyway, that's the end of my tutorial, I hope it was a helpful resource. Source material is Organic Chemistry 12th edition by Solomons, et. al.
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