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Biochemistry question: Which statement is not associated with covalent catalysis by enzymes?
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A transient covalent bond is formed between the enzyme and the substrate. It never involves coenzymes. When the reaction is complete, the enzyme returns to its original state. A new pathway from substrate(s) to product(s) is formed that is faster than the uncatalyzed reaction. I'm thinking it's the second statement? (it never involves coenzymes)
Correct. Covalent catalysis involves the formation of a reversible covalent bond between the enzyme and substrate. Enzymes performing covalent catalysis bear nucleophilic or electrophilic centres.
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