Degradation of cellular mRNA is not associated with __________.

Question

Vocaloid · Answer

- import into the lysosome
- 3'-5' degradation in higher eukaryotes by the exosome
- greatly variable rates in eukaryotes
- resistance to degradation in bacterial mrnas due to the hairpin structure in rho-independent termination of transcription

Vocaloid · Answer

still a bit confused after doing the assigned reading but either A or D?

misty34 · Answer

Most normal eukaryotic cellular mRNAs are not subject to NMD because they only contain a stop codon at the end of the coding region. In contrast, mutant mRNAs that have an in-frame stop codon upstream of the normal stop codon, are recognized by the NMD machinery, leading to mRNA destabilization.