Huntington’s disease is another example of an autosomal dominant disease. The disease allele produces a protein folds incorrectly and destroys certain neurons when the disease proteins aggregate. Symptoms which start at age 35-45 include involuntary movements, decline in mental abilities as well as behavioral and psychiatric problems. Jerry’s paternal grandmother had the disease, but his dad did not. What is the likelihood that Jerry has the disease if his mother is homozygous recessive?

Question

Huntington’s disease is another example of an autosomal dominant disease. The disease allele produces a protein folds incorrectly and destroys certain neurons when the disease proteins aggregate. Symptoms which start at age 35-45 include involuntary movements, decline in mental abilities as well as behavioral and psychiatric problems.  Jerry’s paternal grandmother had the disease, but his dad did not. What is the likelihood that Jerry has the disease if his mother is homozygous recessive?