Question

are microfilaments used in the processes of removing products of golgi body/apparatus.

Answer 1

cause i had an debate with my neuro teacher that they are used, along with the micro-tubules and his question was vague. just want to get my 15points on a test. lol

Answer 2

http://www.jneurosci.org/content/24/50/11291.short

Answer 3

OMG, I don't know if you should trust my answer over your neuro teacher. What level are you? college? HS?

Answer 4

junior in undergraduate

Answer 5

Here is a cite that says they do move things around, Microfilaments and microtubules form a network of fibers that determine cell shape, participate in cell division, move organelles around the cell and form motility structures.
http://www.microbiologytext.com/index.php?module=Book&func=displayarticle&art_id=267

Answer 6

Ok, if you are an ug then you can wow your teacher with this cite I am going to post from NIH's National Library of Medicine, aka PubMed

Answer 7

http://www.ncbi.nlm.nih.gov/pubmed/11576448 See the last bit in the abstract. Actin microfilaments facilitate the retrograde transport from the Golgi complex to the endoplasmic reticulum in mammalian cells.
Valderrama F, Durán JM, Babià T, Barth H, Renau-Piqueras J, Egea G.
Source
Departament de Biologia Cel.lular i Anatomia Patològica, Facultat de Medicina, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, E-08036 Barcelona, Spain.
Abstract
The morphology and subcellular positioning of the Golgi complex depend on both microtubule and actin cytoskeletons. In contrast to microtubules, the role of actin cytoskeleton in the secretory pathway in mammalian cells has not been clearly established. Using cytochalasin D, we have previously shown that microfilaments are not involved in the endoplasmic reticulum-Golgi membrane dynamics. However, it has been reported that, unlike botulinum C2 toxin and latrunculins, cytochalasin D does not produce net depolymerization of actin filaments. Therefore, we have reassessed the functional role of actin microfilaments in the early steps of the biosynthetic pathway using C2 toxin and latrunculin B. The anterograde endoplasmic reticulum-to-Golgi transport monitored with the vesicular stomatitis virus-G protein remained unaltered in cells treated with cytochalasin D, latrunculin B or C2 toxin. Conversely, the brefeldin A-induced Golgi membrane fusion into the endoplasmic reticulum, the Golgi-to-endoplasmic reticulum transport of a Shiga toxin mutant form, and the subcellular distribution of the KDEL receptor were all impaired when actin microfilaments were depolymerized by latrunculin B or C2 toxin. These findings, together with the fact that COPI-coated and uncoated vesicles contain beta/gamma-actin isoforms, indicate that actin microfilaments are involved in the endoplasmic reticulum/Golgi interface, facilitating the retrograde Golgi-to-endoplasmic reticulum membrane transport, which could be mediated by the orchestrated movement of transport intermediates along microtubule and microfilament tracks.

Answer 8

I gave you the cite so you can print it out from PubMEd and look very good.

Answer 9

"... indicate that actin microfilaments are involved in the endoplasmic reticulum/Golgi interface, facilitating the retrograde Golgi-to-endoplasmic reticulum membrane transport, which could be mediated by the orchestrated movement of transport intermediates along microtubule and microfilament tracks."

Answer 10

you are awesome, thank you so much.

Answer 11

Have fun. Comeback and help some one in HS.