why does the chances of baby having down syndrome increases as the age of the women exceeds forty?????????????
In general, in each subsequent pregnancy the chance of having another baby with Down syndrome is about 1 in 100 up to age 40. After age 40, the risk is based on the mother’s age (8). If, however, the first child has translocation Down syndrome, the chance of having another child with Down syndrome may be greatly increased. After birth, the provider takes a blood sample from a baby suspected of having Down syndrome and sends it to a laboratory. The lab does a karyotype (examines the chromosomes) to determine if the baby has Down syndrome and what genetic form of Down syndrome the baby has. This information is important in determining the risk in future pregnancies. The provider may refer parents to a genetic counselor who can explain the results of chromosomal tests in detail, including what the recurrence risks may be in another pregnancy.
thnx
bt wats the reason?
is it becuz the mother is nt able to relaease sum certain chemicals or hormones,sumthin like tat !becuz the ability to produce a chemical or a particular hormone might decrease as u grow older! mayb sumtimes due to high dosage of fertillity drugs!i dunno hashir
its because the eggs are 40 years old. unlike men, women are born with their eggs and once u run out u run out(menopause). so the eggs u r born with are now 40 years old and have had numerous occasions to under-go a mutation that can cause many forms of down syndrome
it's a result of the aging process. all women are born with all of their eggs already. the eggs grow old with you over time. after the age of 35, the eggs have gotten so old that there are more errors in meiosis that result in nondisjunction (failure of a chromosome pair to separate). when a nondisjunction error results in getting an extra chromosome 21, then the baby will have down syndrome. having an extra chromosome from nondisjunction is the most common form of down syndrome. there are a few more genetic mutations that can cause down syndrome and some are related to a mom's age but others are not.
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