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MIT OCW Biology 11 Online
OpenStudy (liliakarina):

What are some of the 'in vivo' functions of the phospholipases, which cleave phospholipids? @Biology

OpenStudy (anonymous):

in vivo means within the cell

OpenStudy (anonymous):

yes and cell is itself means living i didnt mention mam becoz i thought u wer getin cnfused in statement by that word Table 1. Identified Human Phospholipase A1 Group Name Phospholipase activity Triacylglycerol hydrolase activity Enzymatic or Physiological Function Intracellular PA-PLA1 Phosphatidate specific X spermiogenesis p125 Phosphatidate specific ? COPII vesicle organization KIA0725p Phosphatidate specific X membrane trafficking from Golgi Extracellular PS-PLA1 Phosphatidate and lysophosphatidic acid specific X Lysophosphatidic acid production mPA-PLA1α Phosphatidate specific X Lysophosphatidic acid production mPA-PLA1β Phosphatidate specific X Lysophosphatidic acid production Pancreatic lipase tick tick intestinal triacylglycerol hydrolysis Lipoprotein lipase tick tick hydrolyze mainly triacylglycerol in plasma Hepatic lipase tick tick hydrolyze triacylglycerol and phospholipids in plasma Endothelial lipase tick tick hydrolyze mainly phospholipids in plasma Pancreatic lipase related protein-1 ? ? regulate phospholipids in vivo Pancreatic lipase related protein-2 tick tick intestinal triacylglycerol hydrolysis Pancreatic lipase related protein-3 ? ? ? mPA-PLA1, membrane-associated phosphatidic acid preferring phospholipase A1; PA-PLA1, phosphatidic acid specific phospholipase A1; PS-PLA1, phosphatidylserine selective phospholipase A1.

OpenStudy (anonymous):

orry the chart get mess up better u luk this ssite http://lipidlibrary.aocs.org/animbio/phospholipases/index.htm

OpenStudy (anonymous):

now THAT's graphic :D okay, seriously. the main purpose of lipases is digestion. the cell membranes of former living things you eat is made out of phospholipids that need to be digested. that is point A. point B: phospholipases often start the synthesis chains of handy other molecules like prostaglandins (the ouchy-ouchy-molecule) or IP3, a second messenger in cell signal pathways (phospholipase C). point C: many toxins of snakes (or bees, for that matter) contain phospholipase A2. the lipase will digest the cell membranes and as such kill smaller organisms by poking holes into their cell membranes. I hope I could help. :-)

OpenStudy (liliakarina):

Thanks, Heena and Schleifspur. You did help :D.

OpenStudy (anonymous):

well i dunno more about it i just posted a link if it help u den ur thnx is accepted coz den i deserve it :)

OpenStudy (liliakarina):

It's okay

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