Question

what is maturation promoting factor. can someone give a simple description about it..

Answer 1

Maturation promoting factor is the 'generic' name given to to a heterodimer - a macromolecule made of two different protein subunits - composed of cyclin B and cyclin dependent kinase 1. The cyclin is a regulatory subunit; the kinase is the catalyic subunit.

When conditions are 'right' for the cell to leave G2 and divide, the complex is activated by removal of a phosphate group attached to the cyclin. It assumes its active conformation and phosphorylates various proteins, all of which need to be phosphorylated for the cell to head on into mitosis.

Answer 2

A very good question, thanks!