Question

what a difference between prokaryotes and eukaryotes?

Answer 1

There are many differences, but the main one is that eukaryotes have membrane-bound organelles like mitochondria and chloroplasts and a nucleus while prokaryotes do not.

Answer 2

Prokaryotes have no nucleus but eukaryotes have
prokaryotes have circular chromosome, eukaryotes have linear chromosome
prokaryotes have 70s ribosome, but eukaryotes have both 70s and 80s
ribosome prokaryotes' cell division is binary fission but eukaryotes' cell division is mitosis
prokaryotes have one type of RNA polymerase but eukaryotes have 3 types
prokaryotes have no junk DNA (eg intron, parasitic DNA) but eukaryotes have
prokaryotes are small because it's diffusion limited, eukaryotes are large so they use cytoplasmic streaming

I hope this helps