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Biology 15 Online
OpenStudy (anonymous):

How is the inhibition of protein synthesis in prokaryotes? Only in prokariotes, very important.

OpenStudy (anonymous):

try rephrasing the question, cause the question u gave is going to require an article

OpenStudy (anonymous):

anyway, let me give an example with bacteria which is a prokaryote, inhibition of protein synthesis can be very lethal in any form of life whether prokaryote or not Inhition of protein systhesis is the act of stopping, slowing or blocking the production of essential protein in the ribosome of an organism, hence interfering with its survival and growth of cell. A lot of antibacterial durgs work this way and they usually attack the ribosome. U can read up more on this stuff i got

OpenStudy (anonymous):

Yes, that's true sorry, English isn't my first language. I know about antibacterial drugs but is there another way? Again, sorry for my English

OpenStudy (goformit100):

No worries English dosen't matter in Science Subject. The thing matters is the concept.

OpenStudy (anonymous):

well, when i say anti biotic i don't just mean drugs Anything that can inhibit protein synthesis in an organism can result in death and other abnormalities and is therefore anti to that organism, some of the inhibitors, the organism they affect and their action include 1. Tetracycline prokaryotic Inhibits aminoacyl-tRNA binding 2. Penicillin prokaryotic Inhibits transpeptidation enzymes involved in the cross-linking of polysacchride chains of the bacterial cell wall peptidoglycan 3. Chloramphenicol prokaryotic Binds to 50S subunit, blocks peptidyl transferase activity 4. Erythromycin prokaryotic Binds to 50S subunit, blocks peptidyl transferase activity 5. Rifampin prokaryotic Blocks RNA synthesis by binding to and inhibiting the DNA-dependent RNA polymerase 6. Bacitran prokaryotic Inhibits cell wall synthesis by interferring with action of the lipid carrier that transports wall precursors accross plasma membrane. 7. Thiostrepton prokaryotic Inhibits ribosome-dependent EF-Tu and EF-G GTPase 8. Puromycin Prokaryotic and eukaryotic Aminoacyl-tRNA analog, which acts as a peptidyl acceptor, aborting further peptide elongation 9. Sulfonamides prokaryotic Inhibit folic acid synthesis by competition with p-aminobenzoic acid 10. Streptomycin prokaryotic codon misreading, insertion of improper amino acid Prevents formation of initiation complex

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