A married couple, both of whom are heterozygous for the cystic fibrosis gene, seek your counsel concerning the probability of their having a child with the cystic fibrosis disease. Using a Punnett Square, determine the probability
Do you know how to make a Punnett Square? Because I can tell you that cystic fibrosis is a recessive phenotype. A recessive disorder.
Ya but they do not want that tho. A married couple, both of whom are heterozygous for the cystic fibrosis gene, seek your counsel concerning the probability of their having a child with the cystic fibrosis disease. Using a Punnett Square, determine the probability and then write a paragraph explaining their predicament in full detail.
Yes I read all of that. If you make a Punnett Square, using the information that I gave you, then you will have your answer. Do you know how to make a Punnett Square?
Let's start here: If both parents are heterozygous for the cystic fibrosis gene, what are both of their genotypes? We need to know their genotypes before we make the Punnett Square.
Right, but they do not tell me that. I guess I can make it up.
I'm not asking for what they tell you. I'm asking for your answer. You can use any letters you want, to represent the alleles for the phenotype.
Do you know what "heterozygous" means?
Yes, I know what it means.
Okay. So now we need a letter of the alphabet, to represent the alleles. Let's use the letters ( A ) and ( a ). ( A ) represents a normal gene. ( a ) represents a mutated gene. If both of the parents are heterozygous, what are their genotypes?
Do you know what a "genotype" is?
The genotype is the genetic makeup of a cell, an organism, or an individual
Yes, that's the definition of "genotype." So, can you tell me what the genotypes of the parents are going to be?
Listen, I know what the question is asking for. And I think it's pretty obvious I'm not going to just give you the answer. But I'm trying to lead you to the answer. Step by step. Are you going to work with me?
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