what are the different types of cells involved in bone formation/break down and their functions and locations?
Osteoblasts: Bone forming cell. Osteoclast:Bone resorption. Osteoblasts bone forming cells are located near the surface of bones/ They're responsible for making osteoid,which consists mainly of collagen. The osteoblasts then secrete alkaline phosphatase to create sites for calcium and phosphate deposition, which allows crystals of bone mineral to grow at these sites. The osteoid becomes mineralised, thus forming bone. Osteoclast: Multinucleated cells responsible for bone resorption. They travel to specific sites on the surface of bone and secrete acid phosphatase, which unfixes the calcium in mineralised bone to break it down.
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