Question

a gene has a base sequence of GTC. due to a mutation, the base sequence changes to GTG.


what are the bases of mRNA coded for by this section of DNA, before mutation??? hint: in RNA, A pairs with U

Answer 1

also what are the bases of mRNA codes for by this section of DNA, after the mutation???

Answer 2

also what amino acid is coded for by this sequence before the mutation????

Answer 3

also what amino acid i scoded for by this sequence before the mutation???

Answer 4

also is this a silent mutation or a missense mutation???????

Answer 5

Hello @danielwright2414 !

Before Mutation -----> mRNA CUG
After Mutation ------> mRNA CUC

Both will code for Leucine

Answer 6

also what is the difference between a missense mutation and a silent mutation???

Answer 7

A missense mutation is a point mutation in which a single nucleotide change results in a codon that codes for a different amino acid.

Answer 8

Silent mutations are DNA mutations that do not significantly alter the phenotype of the organism in which they occur.

Answer 9

The example given in the question is an example of Silence Mutation

Answer 10

Now suppose if GTC would have changed into GTA then mRNA produced would hav been CAU. This mRNA produces Histidine

Answer 11

Now this is an example of Missense Mutation. Got it ?

Answer 12

yep thanks i have a few more questions

Answer 13

ok

Answer 14

what amino acid is coded for by this sequence before the mutation?

Answer 15

and after the mutation

Answer 16

which sequence ?

Answer 17

the one i gave you in the posted question

Answer 18

Wait

Answer 19

alrighty

Answer 20

Sorrry for that..got a call

Answer 21

its alright

Answer 22

\(\huge\bf Rectification\)
\(\color{blue}{\text{Originally Posted by}}\) @Abhisar
Hello @danielwright2414 !

Before Mutation -----> mRNA CAG -----> Glutamine
After Mutation ------> mRNA CAC ------> Histidine

\(\color{blue}{\text{End of Quote}}\)

Answer 23

So, the example given in the question is of Missense mutation

Answer 24

Rules for converting DNA into mRNA
A--->U
G<--->C

Answer 25

is this sequence a silent or missense mutation

Answer 26

Missense Mutation, check urself. Read the defination i told u

Answer 27

Sequence before and after mutation are encoding for different amino acids now

Answer 28

r uh getting my points ?

Answer 29

i am now lol, for a moment there you lost me thanks again.

Answer 30

r uh sure uh got it ?

Answer 31

yep i have it all written down so i remember

Answer 32

ohkay that's superb !

Answer 33

\(\color{green}{\huge\ddot\smile}\)

Answer 34

lol thanks :)
but i still have 3 more questions to ask if thats ok

Answer 35

Yeah go ahead !

Answer 36

if the strand of dna with the sequence GTA mutated to GTG, would it be silent or missense? & if the strand of dna with the sequence TTA mutated to TTG, would this be a silent or missense? & if the strand of dna with the sequence TGA mutated to GGA, would this be a silent or missense??????? sorry im not very good at these questions....

Answer 37

It's the same kind of question !
I'll urge uh to try them out first

Answer 38

ive been working on these questions for 2 weeks

Answer 39

ohkay, let's work it out together

Answer 40

alrighty

Answer 41

GTA will code for CAU

Answer 42

GTG will code for CAC

Answer 43

CAU will code for Histamine and so will CAC

Answer 44

ok ummm uh u lost me kind of...... wait never mind i got it thanks

Answer 45

Now it's ur job to tell me if it's silent or missense

Answer 46

are uh getting those conversions ?

Answer 47

yep and its missense

Answer 48

How ?

Answer 49

\(\color{blue}{\text{Originally Posted by}}\) @Abhisar
A missense mutation is a point mutation in which a single nucleotide change results in a codon that codes for a different amino acid.
\(\color{blue}{\text{End of Quote}}\)

Answer 50

ok maybe im wrong then idk

Answer 51

The mutation might hav changed the base pair but they are still coding for the same amino acid i.e Histidine

Answer 52

*pls ignore histamine above, it's a typo

Answer 53

Now say honestly r uh getting or should i explain more elaborately

Answer 54

please explain

Answer 55

ohkay, In ur first question GTC mutated to GTG ryt ?

Answer 56

yeah

Answer 57

GTC codes for mRNA CAG which in turn codes for Glutamine amino acid

Answer 58

got this ?

Answer 59

ya

Answer 60

Now GTG codes for CAC wich in turn codes for Histidine

Answer 61

ok ?

Answer 62

yep

Answer 63

This means that before mutation glutamine was being synthesised but after mutation histidine is being synthesised. ok ?

Answer 64

k

Answer 65

Now read the definition of missense mutation

Answer 66

\(\color{blue}{\text{Originally Posted by}}\) @Abhisar
A missense mutation is a point mutation in which a single nucleotide change results in a codon that codes for a different amino acid.
\(\color{blue}{\text{End of Quote}}\)

Answer 67

ohhhh so it is missence because each one is transforming only one other into a different sequence

Answer 68

xactly different amino acid !

Answer 69

Now in ur second question, both after and before mutation same amino acid is eing produced so it'a a silent mutation

Answer 70

brb gonna eat

Answer 71

LOL

Answer 72

ohkay !!

Answer 73

k im back

Answer 74

are you there????

Answer 75

yep

Answer 76

alright next question please

Answer 77

ohkay..post it as new one

Answer 78

for that u'll have to first close this one

Answer 79

It's against the \(\large\sf\color{red}{\underline{\href{ /code-of-conduct}{Code~of~conduct}}}\) of OS to post multiple question in single thread