Question

what part of the gene (DNA) sequence is responsible for controlling when transcription can occur?

Answer 1

Gene regulation usually occurs after the promoter region
Gene enhancement is before the promoter region.

Answer 2

He is write but here is more of an answer A defining feature of transcription factors is that they contain one or more DNA-binding domains (DBDs), which attach to specific sequences of DNA adjacent to the genes that they regulate. Additional proteins such as coactivators, chromatin remodelers, histone acetylases, deacetylases, kinases, and methylases, while also playing crucial roles in gene regulation, lack DNA-binding domains, and, therefore, are not classified as transcription factors.