Question

How does a mutation in the p53 protein cause cancer cells to divide uncontrollably?

(Select all that apply.)

The cell cycle cannot be halted if DNA damage is detected.
Cells with damaged DNA are not signaled to self-destruct.
Two of the three checkpoints no longer work.
Cytokinesis occurs after each phase of the cycle instead of just after mitosis.

Answer 1

The cell cycle cannot be halted if DNA damage is detected.
This is because if the DNA is damaged, then the nucleus is also damaged. Therefore, the cells won't have the organelle to direct them on what to do. Instead, the cells roam around uncontrollably.

Answer 2

So A and B? @excellency?

Answer 3

No wait just A