Question

Orgo II Tutorial: Epoxide Synthesis & Reactions

Answer 1

\({\bf{Synthesis:}}\) uses mCPBA (memorize the structure of this compound and know which oxygen gets donated to the alkene)

Answer 2

syn addition; produces isomers from trans alkenes but only one product from cis alkenes

Answer 3

\({\bf{Ring-opening:}}\) behaves differently in acidic vs basic conditions (be able to draw these mechanisms)

Answer 4

this mechanism can also occur under basic conditions BUT requires a strong nucleophile like an alkoxide/hydroxide via SN2 (consider hindrance)

Answer 5

Anyway, that's the end of my tutorial, I hope it was a helpful resource. Source material is Organic Chemistry 12th edition by Solomons, et. al.