Question

i understand that the ribisomes read the base triplets at a time as the mrna strand slides through the ribosome but how does the the trna, carrying a paticular amino acid, know exactly where to drop in order to bind to the codon pair on the mrna strand? does the trna receive some sort of a signal frm the ribosome as it reads the mrna telling it exactly where to bind or does the trna use the amino acid its carrying to locate the codon pair since a particular codon can only correspond with a particular amino acid?

Answer 1

The ribosome slides along an mRNA translating it, it exposes 3 bases at a time (a codon) and anything that can bind to that codon will.

Imagine you had a piece of paper with a bunch of letters types on it:
ATGATGGGTAGCC

Now you take a note card and cut a hole in the middle such that only 3 letters will be seen through the hole at a time. You slide the note card along the paper revealing 3 letters at a time. (-'s indicate hidden letters)

ATG---------
then
---ATG------
then
------GGT---

the tRNA with the opposite sequence will latch onto those exposed bases.

The tRNA doesn't really get a signal it is just sort of drawn to the opposite strands so will latch onto them as soon as the ribosome revels them.

Answer 2

STELLAR EXPLANATION...BUT HOW DOES THE TRNA KNOW EXACTLY WHAT AMINO ACID TO BIND WITH WITH ITS MOLECULAR HOOK IN THE CYTOPLASM BEFORE EVEN REACHING THE RIBOSOME? DOES THE TRNA USE ITS ANTICODON TO CAPTURE THE RIGHT AMINO ACID BECAUSE IF NOT POSITIONED WITH THE RIGHT AMINO ACID, DISCREPANCY COULD SET IN FURTHER IN TRANSLATION.

Answer 3

So the cell is basically a big sack of molecules constantly bumping into each other randomly. Sometimes when two of those molecules hit, if enough energy is present, then they will bind.

The ribosome basically exposes that codon, so other molecules can randomly hit it. Some of those molecules will be tRNA. So, if the correct tRNA hits a codon then enough (just enough) energy is present for the amino acid to be added to the peptide. If the tRNA is not quite right (like the codon is GGT but the anticodon is AAT) then it will require extra energy to stay there, which the ribosome doesn't have, and it is basically repelled back away from the ribosome. But if the codons do match (GGT and CCA) then the tRNA is in a lower energy state (the two chunks of RNA want to stick together) and the ribosome can add the amino acid to the peptide.

Answer 4

YOU LOST ME ON THE FIRST PARAGRAPH BUT EVERYTHING ELSE SOUNDS ACCESIBLE..SO WHAT YOU ARE BASICALLY SAYING IS THAT THERE MUST BE A CORRECT PAIRING BETWEEN ANTICODON AND CODON TO DRIVE AN ADDITION OF THE AMINO ACID TO THE AMINO ACID CHAIN? THAT MEANS THAT THE RIGHT BINDING IS EQUALIVALENT TO ENOUGH ENERGY FOR ATTACHMENT OF AMINO ACIDS? FOR FUTURE REFERENCE, THERE ARE NO THYMINES IN THE RNA SOCIETY, THEY ARE REPLACED WITH URACILS...YOU COMMITED THAT BLUNDER IN YOUR EXPLANATION BUT IM SURE YOU KNEW, IT WAS JUST A CARELESS MISTAKE...

Answer 5

You got the idea, i make that T/A error all the time.

The first paragraph is just saying that tRNA's will randomly try to bind to the codon until the right one fits.