What do you think happens to the cell cycle in a tumor cell (cancer cell) You know
That tumors can grow very fast. Is that because of changes in the cell cycle of an individual cancer cell or changes in the whole group of cancer cells? Do you think that a cancer cell goes through its cell cycle faster, slower, or the at same rate as a normal cell?

Question

What do you think happens to the cell cycle in a tumor cell (cancer cell) You know 
That tumors can grow very fast. Is that because of changes in the cell cycle of an individual cancer cell or changes in the whole group of cancer cells? Do you think that a cancer cell goes through its cell cycle faster, slower, or the at same rate as a normal cell?

anonymous · Answer

A disregulation of the cell cycle components may lead to tumor formation. As mentioned above, some genes like the cell cycle inhibitors, RB, p53 etc., when they mutate, may cause the cell to multiply uncontrollably, forming a tumor. Although the duration of cell cycle in tumor cells is equal to or longer than that of normal cell cycle, the proportion of cells that are in active cell division (versus quiescent cells in G0 phase) in tumors is much higher than that in normal tissue. Thus there is a net increase in cell number as the number of cells that die by apoptosis or senescence remains the same... http://en.wikipedia.org/wiki/Cell_cycle#Role_in_tumor_formation

anonymous · Answer

Although the duration of cell cycle in tumor cells is equal to or longer than that of normal cell cycle, the proportion of cells that are in active cell division (versus quiescent cells in G0 phase) in tumors is much higher than that in normal tissue. Thus there is a net increase in cell number