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Biology 15 Online
OpenStudy (anonymous):

why the brain cell dont divide while all our cell divide except nerve cells

OpenStudy (anonymous):

hey Zhang why do the brain cell not dividing

OpenStudy (anonymous):

because the brain cell's stored the knowledge that you have gained in your life , That mean if they divide you will lose your knowledge

OpenStudy (anonymous):

The general rule about brain cells is that they don't divide because that are terminally differentiated. This means they have a particular gene expression pattern and unlike stem cells they have no capacity to divide. This lack of dividing potential probably comes from gene expression. Note that if oncogenes are activated in brain cells then cells can become cancerous and brain tumours arise - glioblastoma and medulloblastoma are two types of brain cancer. The mechanism by which the genes are controlled is a hot topic in research - many medulloblastomas involve the reduction of activity of the tumour suppressor gene p53. I hope this helps to clear things up for you - I'd say brain cells don't divide because that's the way we have evolved - look up teleology if you like.

OpenStudy (anonymous):

Great answers! Just want to bring up - in a very small set of cases, neurons do indeed divide. Somewhat recent research has overturned previously held notions about the brain. I don't know much about this field of bio, but here's a good start if you're interested: http://en.wikipedia.org/wiki/Adult_neurogenesis

OpenStudy (anonymous):

thnks fr u answer...bt not satisfied with u answer

OpenStudy (anonymous):

but this is nt the correct answer

OpenStudy (blues):

Haseeb, I'm sorry that you are not satisfied with the answers given by ebaxter and kma230. As usual, their answers are correct, thorough and lucid. If you would like to explain why you think their answer is incorrect or ask for clarification, please do so.

OpenStudy (anonymous):

Just wanted to jump in here and second what @kma230 said - adult neurons DO replicate, but it's relatively uncommon, compared to immature and growing stages of life, and so far, that process is not well understood. @ebaxter01 provides the commonly-held and well-researched answer to why they don't replicate and like @blues, I gotta agree with both of them!

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