can someone explain to me about epistasis?
Epistasis occurs when you have two different genes that affect the same trait. These genes may encode enzymes in the same pathway. Let's say Gene A encodes enzyme A which makes a blue pigment in flowers. And Gene B encodes enzyme B which turns the blue pigment into a red pigment. The wild type flower is red, because both genes A and B are functional. If gene B is non-functional (genotype = AAbb, where the recessive b indicates a non-functional allele of gene B), the flowers will be blue. If gene A is nonfunctional, then the flowers will be white because no pigment is made. In that case, both aaBB and aabb genotypes produce white flowers. We say that gene A is epistatic to gene B because the genotype at A can hide the genotype of gene B.
Epistasis - the interaction between two or more genes to control a single phenotype. Example: The B allele in guinea pigs makes black fur, so any pig with a dominant allele is black. However, the P gene determines the deposition of pigment, so that without a P allele, pigment is not deposited. Not matter how many B alleles ther are, there is no black fur without a P allele. Guinea pigs with the genotype BBpp are, therefore, white, and those that are BBPp are black. The P gene is epistatic to the B gene.
thanks guys....u rock
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