Cells in the pancreas are responsible for producing insulin, a protein excreted from the cell and used to help regulate blood sugar levels. Since the protein will be released out of the cell in which it is made, which of the cell's ribosomes are most likely involved in its production?

Question

anonymous · Answer

Do any of these have multiple choice by any chance ?

anonymous · Answer

yes

anonymous · Answer

..Can you write them out?

anonymous · Answer

The ribosomes lining the cell membrane will make it so it can be sent out of the cell more quickly.

The ribosomes surrounding the Golgi apparatus will make it so it can be more easily captured and wrapped in membrane.

The ribosomes on the endoplasmic reticulum will make it so it can be wrapped in membrane and sent to the Golgi apparatus.

The ribosomes floating in the cytoplasm will make it so it can be bent into the correct shape.

anonymous · Answer

I think it's the 3rd one...but i may be wrong...

anonymous · Answer

that was my guess too

anonymous · Answer

I believe you are all correct.

Ribosomes are more or less located in two general areas - freely in the cytosol or attached to the rough endoplasmic reticulum. Choices A and B fit neither of these categories and so can be eliminated directly. Now, you know that these proteins will be secreted. Keep in mind then that ribosomes associated with the ER create their proteins in the lumen or interior of the ER. The ER then packages these proteins into vesicles and secretes them to the Golgi, which secretes them to the membrane.

So, ER-associated ribosomes are bound by vesicles, and free ribosomes in the cytosol create proteins are not. The former is associated with secreted proteins and membrane proteins, the latter with free-standing proteins like histones or the catalytic enzymes of glycolysis.