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can anyone explain about the differences between ASO(allele specific oligonucleotide hybridization) and ASA(allele specific amplification)?? it makes my head exploded T T I will have exams tmr
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An allele-specific oligonucleotide (ASO) is a short piece of synthetic DNA complementary to the sequence of a variable target DNA. It acts as a probe for the presence of the target in a Southern blot assay or, more commonly, in the simpler Dot blot assay. It is a common tool used in genetic testing, forensics, and Molecular Biology research. Source: http://en.wikipedia.org/wiki/Allele-specific_oligonucleotide i couldn't find much info about ASA. GOOD LUCK with your exams!!!!!!!
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