what is the definition of a proto oncogene and a tumor suppressor gene in cell division?

Question

blues · Answer

In general, a proto-oncogene is a non-mutant copy of a gene often mutated in cancer. Random mutations accumulate in these genes and when they do, the gene becomes an oncogene which promotes the cell becoming cancerous

A tumor suppressor gene codes for a protein which somehow inhibits the cell from becoming cancerous.

And the definition of whether a cell is 'transformed' or become a cancer cell is whether it can undergo unchecked cell division...

anonymous · Answer

does proto oncogene mutate? I think so

blues · Answer

Most point mutations - mutations involving just one base - happen at random. Sometimes other sorts of mutations - such as chunks of DNA being cut out of one chromosome and being stuck on other, called 'translocations' - do not happen at random but don't worry about that.

anonymous · Answer

so mutation happens?

anonymous · Answer

what is the original source of taxol?